Why you should Love the Unsubscribe Button, Not hate it.

For a starters time costs money and money costs time, already you are in a conundrum.
So please don't fret about the unsubscribe button, it will in the long run save you time and money.

Why would you want to waste time on people who do not want to listen? 
Why would you want to waste any money on the people who don't care?

Simple, don't. With the unsubscribe button you can use it to your advantage, when a person decides 'No more' to your newsletters don't get upset or offended but simply ask them why they did not enjoy them. Perhaps say your final good byes so you do not part on bad terms, try to win them back with an incentive like the heart of a loved one who is about to board that plane forever. Never fully give up on the final hurdle. 

Or just simply ask them to fill out a survey as to how you could improve your services for future references. 

The ultimate goal here is to not let them hit that dreaded Spam button. So do not under any circumstances make it difficult for them to leave. 

Not sure where to place the unsubscribe button? 
Most businesses make it clear and easy to find at the bottom of the newsletter. 
At the risk of sounding contradicting it is risky making your unsubscribe button easily accessible however remember that it is better than the consequence. If you receive too many marked spam emails this will get back to your service provider and it is less likely your email will be delivered to the inbox.